Hours after the White House added safety precautions against the coronavirus for the president and his staff Sunday, Trump administration officials denied a report that Vice President Mike Pence is self-isolating. Meanwhile, Sen. Lamar Alexander of Tennessee announced he will self-quarantine for two weeks after an aide tested positive.

In a far-from-typical Mother’s Day, social distancing measures kept many families from celebrating together in the U.S., which has recorded nearly one-third of the world’s cases. However, unrest about lockdown restrictions had businesses in Pennsylvania and Ohio defying state orders.

Earlier in the day, a top economic adviser predicted unemployment levels could exceed 20%, and New York revealed new rules for nursing homes, where many of the coronavirus deaths in the state have occurred.

There were nearly 80,000 deaths and more than 1.3 million confirmed coronavirus cases in the U.S. as on Sunday, according to the John Hopkins University data dashboard. Worldwide, the virus has killed more than 282,000 people and infected almost 4.1 million.

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Here are some of the most significant developments to know Sunday:

Predicting that the worst job losses would come in “May or June,” White House economic adviser Kevin Hassett said the unemployment rate could rise above 20%.
The White House is taking extra precautions after aides to the president and vice president tested positive for the coronavirus last week.
New York state is instituting new rules for nursing homes in an effort to protect what Gov. Andrew Cuomo called “a congregation of vulnerable people.’’
Dr. Anthony Fauci is taking “appropriate precautions,” and two other White House coronavirus task force members will self-quarantine for two weeks after being in contact with someone who tested positive for the virus.
What we’re talking about today: It’s Mother’s Day, and it’s easy to see what the pandemic has taken. But it has also brought grown children home.

Does wearing a mask weaken the immune system? We rate the claim “false,” even though you may have heard it in a debunked viral video.