About 1,000 Boston residents will be tested for coronavirus antibodies as part of a study hoping to track how many people living in hard-hit neighborhoods may have already been infected by COVID-19 without ever developing clear symptoms.

The program, which Mayor Marty Walsh announced Sunday in partnership with Massachusetts General Hospital, will focus its testing on people living in East Boston, Roslindale, and parts of Dorchester.

“It is our hope that by conducting this testing, we as a collective city will get a better understanding of the true prevalence of COVID-19 in our community,” Walsh said in a statement. “The more we can expand our testing, the more we can learn how to use our medical resources more efficiently, and how we need to focus our current efforts to contain the virus.”

Nationally, the CDC has estimated that 25% of people with COVID-19 are asymptomatic and may be a carrier of the virus, unknowingly infecting others.

City officials have already started reaching out to potential asymptomatic Boston residents, who will be randomly selected this week, and participation will be available on a first-come, first-served basis, according to the mayor’s office.

Anyone involved in the study will be tested, free of charge, for both COVID-19 and the COVID-19 antibodies. Those who test positive for either will be given clear guidance on how to care for themselves and those close to them, the city said in its statement.

Walsh’s office said the program is expected to see completion by this Friday, May 1, and promised to publicly release the data, including the numbers and percentage of residents within the hard-hit neighborhoods who test positive for the virus or for COVID-19 antibodies.